Omicia Wins UK’s 100,000 Genomes Project as Clinical Interpretation Provider

Omicia Opal Platform to Bring Genomics to Mainstream Healthcare in UK National Initiative

Oakland, CA — Omicia, the leading clinical genomics company, today announced that it has been selected by Genomics England to provide clinical interpretation services for the 100,000 Genomes Project. For the first phase of the project Illumina will provide sequencing services, while Omicia will provide interpretation and clinical reports.

Genomics England leads the UK’s national initiative to integrate genomics-based precision medicine into routine healthcare. Recognizing the significant challenge of generating clinically relevant information from massive amounts of genomic data, Genomics England launched a rigorous evaluation process to select the companies most capable of identifying the genetic cause of rare disease and cancer in patient samples. Omicia was selected out of 28 companies competing in the interpretation assessment and is now one of four companies that will provide annotation, interpretation, and reporting services. The first phase of the 100,000 Genomes Project will include 8,000 patients, growing to 100,000 by 2017.

“Omicia is proud to partner with the pioneering Genomics England project and we look forward to working closely with the members of the Genomics England Clinical Interpretation Partnership,” said Martin Reese, Ph.D., CSO and Founder of Omicia. “Clinicians and researchers recognize that interpreting genome sequencing data is the biggest challenge to bringing genomics to routine clinical testing, therapy selection, and clinical trials. Omicia is delighted to contribute our expertise in genome interpretation, combining the Opal platform with Illumina’s next-generation sequencing services to benefit patients in the UK’s National Health System (NHS).”

Augusto Rendon, Ph.D., Director of Bioinformatics at Genomics England, commented, “This is an important milestone for the project. We are looking to provide high quality variant interpretation to assist clinicians within the NHS and these companies will enable us to deliver this service. We look forward to working with each of the successful companies over the next year.”

Genomics England estimates that one in 17 people are born with, or will develop, a rare disease during their lifetime. More than 80 percent of those rare diseases have an identified genetic component. Genomics England recently announced the first patients to be diagnosed with genetic disease as part of the 100,000 Genomes Project: individuals with kidney disease and peripheral neuropathy. With these diagnoses patients can receive more personalized care. Omicia is an innovator in genomic disease diagnostics; the company’s VAAST algorithm was used in the variant interpretation and discovery of the gene for Ogden Syndrome, one of the first disease genes identified using next-generation sequencing (NGS).

Omicia’s Opal platform is the industry-leading clinical genome interpretation platform, with widespread adoption at premier genomic centers, hospitals, clinical labs, and academic centers.

The company is launching NGS products with Laboratory Corporation of America® Holdings (LabCorp®) (NYSE: LH), the world’s leading healthcare diagnostics company, to be used for clinical diagnostics and drug development support. In addition, an ongoing Omicia collaboration with the University of Utah has produced numerous bioinformatics breakthroughs including the VAAST and Phevor algorithms.

“Omicia’s Opal platform optimizes genomic data interpretation and enables clinical decision support for physicians and their patients,” said Charlene Son Rigby, VP Products and Genomics England Project Leader for Omicia. “Omicia works with clinical labs and hospitals to help them realize the promise of genomic medicine to improve clinical outcomes. Now, we are honored to deploy our platform to support the 100,000 Genomes Project in conjunction with the Genomic Medicine Centres.”

About Omicia, Inc.

Omicia delivers genome analysis solutions for research, diagnostic, and clinical applications. Our market-leading software platform enables analysis, interpretation, and reporting on genomic data to expedite diagnosis and improve medical outcomes. Omicia’s products are in use at more than 500 world-class academic and clinical institutions worldwide. By accelerating understanding of the genetic basis of disease, drug response, and health, Omicia is unlocking the potential of individualized medicine. Headquartered in Oakland, California, Omicia was founded by renowned industry veterans with a deep understanding of technology, genomics, and diagnostics. Investors include Artis Ventures, Acadia Woods, Bay City Capital, Buchanan Investments, Casdin Capital, and Yuri Milner. For more information, visit and follow us on Twitter @omicia.

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